| A scientific discussion has been conducted during the whole year of 2006 before the meeting itself and it is divided in 2 steps:
- methodological consensus;
- specific disease consensus.
The Scientific Secretariat had a key role in this process and its operational functions was:
- to identify the main conflicting arguments (such as intra operative peritoneal carcinomatosis staging system);
- to prepare the list of possible solutions and answers to these conflicting points;
- to identify the respective level of experimental and clinical evidence supporting each possible alternatives or solutions;
- to prepare the list of references from the scientific literature.
The medical literature over the past 20 years was reviewed by the Scientific Secretariat (SS). The Medline search path was reported on each document. Some of the most relevant papers on CRS+HIPEC was summarized in different grids. Moreover, a search of the reviews on peritoneal surface malignancies management already available on the internet was made. Based on this process the Scientific Secretariat (SS) elaborated draft documents containing different solutions for each conflicting point according to an evidence-based methodology.
In the first phase of the scientific discussion the Scientific Secretariat has to work together with the International Scientific Committee (ISC) to reach consensus on methodological aspects of the local-regional therapy.
In the second phase, the discussion is based on the specific diseases and the scope is not only the reaching of the consensus on conflicting points, but also the definition of the state of the art and future prospects.
Parallel to these 2 phases a third discussion related to the specialties indirectly involved in the of the local-regional therapy (biology, nutrition, nursing, anesthesiology) has been conducted and coordinated by the ISC to define the state of the art and future prospects.
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